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N-Carbobenzoxy-4-hydroxy-D-2-phenylglycine is a chemical compound that is commonly used as a building block in peptide synthesis. It is specifically used as a protected form of the amino acid D-2-phenylglycine, which can be selectively deprotected to reveal the free amino acid during peptide synthesis. This compound may have potential applications in the synthesis of pharmaceuticals and other biologically active molecules. Additionally, N-Carbobenzoxy-4-hydroxy-D-2-phenylglycine has been found to exhibit antimicrobial properties, making it a potential candidate for drug development. Overall, this compound is an important tool for the synthesis of peptides and the study of protein structure and function.
β-Peptides are an interesting new class ...
Cp?Cobalt(III)-catalyzed enantioselectiv...
The present invention relates to compoun...
The invention discloses a D-hydroxy phen...
D-4-hydroxyphenylglycine
benzyl chloroformate
(R)-2-(((benzyloxy)carbonyl)amino)-2-(4-hydroxyphenyl)acetic acid
| Conditions | Yield |
|---|---|
|
With sodium carbonate; In 1,4-dioxane; water; toluene; at 0 - 20 ℃; for 1.5h;
|
93% |
|
With sodium carbonate; In dichloromethane; water; at 0 - 25 ℃;
|
88% |
|
With sodium hydrogencarbonate; In water; at 18 - 25 ℃; for 2.33333h; Inert atmosphere;
|
53% |
|
With sodium hydrogencarbonate; In water; for 1h;
|
|
|
With potassium hydroxide; In water; at 0 - 20 ℃; for 0.0833333h;
|
benzyloxycarbonyl succinimide
D-4-hydroxyphenylglycine
(R)-2-(((benzyloxy)carbonyl)amino)-2-(4-hydroxyphenyl)acetic acid
| Conditions | Yield |
|---|---|
|
With potassium carbonate; In water; acetone; at 15 - 35 ℃; pH=8-9;
|
95% |
D-4-hydroxyphenylglycine
benzyl chloroformate
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