What is the Z-DEHYDRO-ALA-OME?

Z-DEHYDRO-ALA-OME is , while it's Molecular Formula is C12H13NO4.

What is the CAS number for Z-DEHYDRO-ALA-OME?

The CAS number of Z-DEHYDRO-ALA-OME is 21149-17-7.

What is the Z-DEHYDRO-ALA-OME?

Z-DEHYDRO-ALA-OME is , while it's Molecular Formula is C12H13NO4.

What is the CAS number for Z-DEHYDRO-ALA-OME?

The CAS number of Z-DEHYDRO-ALA-OME is 21149-17-7.

High Purity Methyl2-(((benzyloxy)carbonyl)amino)acrylate 21149-17-7 with Factory Price

Q: What is Z-DEHYDRO-ALA-OME (21149-17-7) used for?

InChI:InChI=1/C12H13NO4/c1-9(11(14)16-2)13-12(15)17-8-10-6-4-3-5-7-10/h3-7H,1,8H2,2H3,(H,13,15)

Product Details

Quick Details

CasNo： 21149-17-7
Molecular Formula： C₁₂H₁₃NO₄
Purity： 99%

High Purity Methyl2-(((benzyloxy)carbonyl)amino)acrylate 21149-17-7 with Factory Price

Molecular Formula:C12H13NO4
Molecular Weight:235.24
Vapor Pressure:2.62E-05mmHg at 25°C
Refractive Index:1.525
Boiling Point:358 °C at 760 mmHg
Flash Point:170.3 °C
PSA：64.63000
Density:1.182 g/cm³
LogP:1.99040

Z-DEHYDRO-ALA-OME(Cas 21149-17-7) Usage

Chemical Properties	White solid
Uses	Methyl2-(((benzyloxy)carbonyl)amino)acrylate has been found to have potential therapeutic applications, including as an antiviral agent and as a treatment for cancer.

IUPAC Name: methyl 2-(phenylmethoxycarbonylamino)prop-2-enoate
Isomeric SMILES: COC(=O)C(=C)NC(=O)OCC1=CC=CC=C1
InChIKey: STFUIEDYPRMRNN-UHFFFAOYSA-N
InChI: InChI=1S/C12H13NO4/c1-9(11(14)16-2)13-12(15)17-8-10-6-4-3-5-7-10/h3-7H,1,8H2,2H3,(H,13,15)

21149-17-7 Relevant articles

Recent advances in the synthesis of polysubstituted 3-pyrazolidinones

U Grošelj, J Svete

, Arkivoc, 2015

First, 3-substituted methyl 2-(benzyloxycarbonylamino)- acrylates 3a–i were prepared by Wittig-Horner condensation of methyl 2- (benzyloxycarbonylamino)-2-(dimethoxyphosphoryl)acetate (2) with aldehydes and ketones following a slightly modified procedure by Schmidt and co-workers.39 Acrylates 3a–i were then treated with excess of N2H4·H2O in an alcohol (MeOH, EtOH, or n PrOH) at 20–100 °C to afford the corresponding 3-pyrazolidinones 4a–i in 23–100% yields (Scheme 1).

3-Imidoallenylphosphonates: In Situ Formation and β-Alkoxylation

Berton, Jan K. E. T.,Heugebaert, Thomas S. A.,Debrouwer, Wouter,Stevens, Christian V.

, p. 208 - 211 (2016)

3-Imidoallenylphosphonates, allenes bear...

Facile access to α,β-dehydroalanine and α,β-dehydroamino butyric acid derivatives from DL-serines and threonines

Yang, Yong-Qing,Ji, Meng-Chen,Lu, Zheng,Jiang, Mao,Huang, Wei-Wei,He, Xue-Zhi

, p. 977 - 982 (2016)

ABSTRACT: Not only α,β-dehydroamino acid...

Conjugate addition of ammo acid side chains to alkynones and alkynoic acid derivatives

Crisp, Geoffrey T.,Millan, Michael J.

, p. 637 - 648 (1998)

Suitably protected amino acids were used...

INTRANASAL PHARMACEUTICAL COMPOSITIONS OF CGRP INHIBITORS

-

Page/Page column 20-21; 25-26, (2021/06/26)

Provided is pharmaceutical composition f...

Catalytic Arylhydroxylation of Dehydroalanine in Continuous Flow for Simple Access to Unnatural Amino Acids

Khan, R. Kashif M.,Zhao, Yang,Scully, Tal D.,Buchwald, Stephen L.

, p. 15215 - 15218 (2018/09/25)

This report discloses the first example ...

21149-17-7 Process route

: 14464-15-4
methyl 2-(benzyloxycarbonylamino)-3-hydroxypropanoate

: 21149-17-7
methyl 2-(benzyloxycarbonylamino)acrylate

Conditions

Conditions	Yield
With dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene; p-toluenesulfonyl chloride; In acetonitrile; at 20 ℃; Molecular sieve;	72%
methyl 2-(benzyloxycarbonylamino)-3-hydroxypropanoate; With dichloroacethyl chloride; triethylamine; In dichloromethane; at 20 ℃; for 1.5h; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; for 4h; Heating;	48%
Multi-step reaction with 2 steps 1: 81 percent / pyridine / CH₂Cl₂ / 2 h / 20 °C 2: 84 percent / K₂CO₃ / dimethylformamide / 1 h / 65 °C With pyridine; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;
Multi-step reaction with 2 steps 1: 58 percent / phosphorus pentachloride / CHCl₃ / 4 h / 0 °C 2: 84 percent / diazabicyclo<5.4.0>undec-7-ene / CHCl₃ / 1 h / 60 °C With phosphorus pentachloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In chloroform;
With methanesulfonyl chloride; triethylamine; In dichloromethane; at 0 - 20 ℃; for 1.33333h;	1.1 g
Multi-step reaction with 2 steps 1.1: triethylamine / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere 1.2: 1 h / 0 °C 2.1: triethylamine / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere With triethylamine; In tetrahydrofuran;

: (S)-methyl 2-(benzyloxycarbonyl)-3-hydroxypropanoate

: 124-63-0
methanesulfonyl chloride

: 21149-17-7
methyl 2-(benzyloxycarbonylamino)acrylate

Conditions

Conditions	Yield
(S)-methyl 2-(benzyloxycarbonyl)-3-hydroxypropanoate; methanesulfonyl chloride; With triethylamine; In dichloromethane; at -15 - 0 ℃; for 0.5h; With methanol; In dichloromethane; at 20 ℃; for 1.5h;	92%