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N-tert-butyl-serineisopropyl ester is commonly used in the pharmaceutical industry as a starting material for the synthesis of various drugs and as a reagent in organic chemistry. It has been found to have potential therapeutic applications, including as an anti-inflammatory agent and as a treatment for cardiovascular diseases.
IUPAC Name: propan-2-yl (2S)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
Isomeric SMILES: CC(C)OC(=O)[C@H](CO)NC(=O)OC(C)(C)C
InChIKey: QVURMCPIMAXTNA-QMMMGPOBSA-N
InChI: InChI=1S/C11H21NO5/c1-7(2)16-9(14)8(6-13)12-10(15)17-11(3,4)5/h7-8,13H,6H2,1-5H3,(H,12,15)/t8-/m0/s1
Starting from (S)-serine, a new method was developed for the synthesis of the N-tert-butyl-serineisopropyl ester in ten steps and with an overall yield of 30%.
isopropyl 2-(tert-butoxycarbonylamino)-3-(methylsulfonyloxy)propanoate
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