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Product Details
| Classification | DrugPortal |
|
Uses |
(2S)-3,3-dimethyl-2-[(2,2,2-trifluoroacetyl)amino]butanoic acid is used as a chiral building block in organic synthesis and in the preparation of pharmaceutical intermediates. |
IUPAC Name: (2S)-3,3-dimethyl-2-[(2,2,2-trifluoroacetyl)amino]butanoic acid
Isomeric SMILES: CC(C)(C)[C@@H](C(=O)O)NC(=O)C(F)(F)F
InChIKey: FCTPLAZWXGEGKO-SCSAIBSYSA-N
InChI: InChI=1S/C8H12F3NO3/c1-7(2,3)4(5(13)14)12-6(15)8(9,10)11/h4H,1-3H3,(H,12,15)(H,13,14)/t4-/m1/s1
Our efforts are focused on the applicati...
L-tert-Leucine
ethyl trifluoroacetate,
N-trifluoroacetyl tert-leucine
| Conditions | Yield |
|---|---|
|
With potassium methanolate; In methanol; at 40 ℃; for 2h;
|
N-trifluoroacetyl tert-leucine
methylamine
N'-trifluoroacetyl-S-tert-leucine N-methylamide
| Conditions | Yield |
|---|---|
|
N-trifluoroacetyl tert-leucine; With Vilsmeier reagent; In ethyl acetate; at -15 ℃; for 2h;
methylamine; In water; ethyl acetate;
|
39.0 g |
L-tert-Leucine
ethyl trifluoroacetate,
(1R,2S,5S)-N-{(1R)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide
(1R,2S,5S)-N-{(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide
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