Your Location:Home >Products >Biochemical Engineering >166108-71-0
Product Details
Uses |
[2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid is a hydrophilic, heterobifunctional spacer. [2-[2-(Fmoc-amino)-ethoxy]- ethoxy]acetic acid (Fmoc-AEEAc-OH, AnaSpec) residues can be used as PEG spacers. [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid is a coupling agent used in the synthesis of polypeptides or peptides. It is useful to attach chromophores. |
Description |
Fmoc-AEEAc-OH. Also known as (PEG)2 or Fmoc-8-amino-3,6-dioxaoctanoic acid, is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. |
Chemical Properties |
White solid |
InChI:InChI=1/C21H23NO6/c23-20(24)14-27-12-11-26-10-9-22-21(25)28-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-8,19H,9-14H2,(H,22,25)(H,23,24)
The first step involved printing a {2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid (Fmoc-AEEA-OH) linker onto an aminopropyltrimethoxysilane (APTS) SAM on silicon. Subsequent …
(TAMRA), (2) a Cys for … {2[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid (PEG) as a spacer between Ub and the unnatural elements. Employing Fmoc-SPPS on a 2-chlorotrityl chloride (2-…
In this regard, Fmoc-β-Ala-OH was chosen as the shorter spacer and Fmoc-AEEAc-OH as the longer spacer. Six-carbon long Fmoc-ε-Ahx-OH will be another choice, even though it …
2-(2-(2-aminoethoxy)ethoxy)ethan-1-ol
8-(9-fluorenylmethyloxycarbonyl-amino)-3,6-dioxaoctanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / water / Inert atmosphere
2: sodium hypochlorite; 2,2,6,6-tetramethyl-piperidine-N-oxyl / dichloromethane / Inert atmosphere
With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium hydrogencarbonate; In dichloromethane; water;
|
8-(9-fluorenylmethoxycarbonylamino)-3,6-dioxaoctanoic acid tert-butyl ester
8-(9-fluorenylmethyloxycarbonyl-amino)-3,6-dioxaoctanoic acid
Conditions | Yield |
---|---|
With trifluoroacetic acid; In dichloromethane; for 2h;
|
100% |
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
[2-(N-2-amino ethoxy)ethoxy] acetic acid
[2-(2-dibenzylaminoethoxy)ethoxy]acetic acid
[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]carbamic acid 9H-fluoren-9-ylmethyl ester
[2-(2-{2-[2-(2-{[2'-(4-hydroxy-phenyl)-6-(4-methyl-piperazin-1-yl)-1H,3'H-[2,5']bibenzoimidazolyl-4-carbonyl]-amino}-ethoxy)-ethoxy]-acetylamino}-ethoxy)-ethoxy]-acetic acid
2'-(4-hydroxy-phenyl)-6-(4-methyl-piperazin-1-yl)-1H,3'H-[2,5']bibenzoimidazolyl-4-carboxylic acid (2-{2-[(2-{2-[(2-{2-[(2-mercapto-ethylcarbamoyl)-methoxy]-ethoxy}-ethylcarbamoyl)-methoxy]-ethoxy}-ethylcarbamoyl)-methoxy]-ethoxy}-ethyl)-amide
CAS:56-12-2
CAS:7531-52-4
CAS:15295-77-9
CAS:71989-18-9