What is the D(-)-Glutamic acid?

D(-)-Glutamic acid is white crystalline powder, while it's Molecular Formula is C5H9NO4. white crystalline powder D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.

What is the CAS number for D(-)-Glutamic acid?

The CAS number of D(-)-Glutamic acid is 6893-26-1.

What is D(-)-Glutamic acid (6893-26-1) used for?

InChI:InChI=1/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m1/s1

What is the D(-)-Glutamic acid?

D(-)-Glutamic acid is white crystalline powder, while it's Molecular Formula is C5H9NO4. white crystalline powder D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.

What is the CAS number for D(-)-Glutamic acid?

The CAS number of D(-)-Glutamic acid is 6893-26-1.

What is D(-)-Glutamic acid (6893-26-1) used for?

InChI:InChI=1/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m1/s1

Food Grade D-Glutamic acid 6893-26-1 In Medicine

Product Details

Quick Details

CasNo： 6893-26-1
Molecular Formula： C₅H₉NO₄
Appearance： white crystalline powder
Purity： 99%

Food Grade D-Glutamic acid 6893-26-1 In Medicine

Molecular Formula:C5H9NO4
Molecular Weight:147.131
Appearance/Colour:white crystalline powder
Vapor Pressure:2.55E-05mmHg at 25°C
Melting Point:200-202 °C
Refractive Index:1.4210 (estimate)
Boiling Point:333.8 °C at 760 mmHg
PKA:pK1:2.162(＋1);pK2:4.272(0);pK3:9.358(－1) (25°C)
Flash Point:155.7 °C
PSA：100.62000
Density:1.409 g/cm³
LogP:-0.03660

D(-)-Glutamic acid(Cas 6893-26-1) Usage

Chemical Properties	White cryst. powder
Uses	D-Glutamic Acid is the unnatural (R)-enantiomer of Glutamic Acid, a non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. D-glutamic acid is an optically active form of glutamic acid having D-configuration. It helps in the growth of Lactobacillus arabinosus. It can inhibit the IgE binding to peanut allergens. Glutamic Acid is also a key molecule in cellular metabolism.
Definition	ChEBI: An optically active form of glutamic acid having D-configuration.
General Description	Glutamic acid is the most common excitatory neurotransmitter in the central nervous system. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.
Biological Activity	Excitatory amino acid acting at NMDA receptors; less active than the L-isomer.
Biochem/physiol Actions	Unnatural isomer of glutamic acid.

Isomeric SMILES: C(CC(=O)O)[C@H](C(=O)O)N
InChIKey: WHUUTDBJXJRKMK-GSVOUGTGSA-N
InChI: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1

6893-26-1 Relevant articles

Electrochemical synthesis of (poly) dimethoxyaniline on glassy carbon electrodes and their applications in the detection of L-and D-glutamic acids

Xin Zeng1,2, Nan Li3,1 and Jichang Wang3,2

Journal of The Electrochemical Society, Volume 166, Number 9

Using cyclic voltammetry method, the anodic peak currents were found to have a linear relationship with the concentration of glutamic acids within the range between 0.5 and 15.0 mM, with a detection limit of 0.11 mM for L-glutamic acid and 0.26 mM for D-glutamic acid. The device-to-device reproducibility is great, confirming the robustness of this modification method.

Plasma metabolites Xanthine, 4-Pyridoxate, and d-glutamic acid as novel potential biomarkers for pulmonary tuberculosis

Author links open overlay panelHuai Huang a b, Li-Ying Shi c, Li-Liang Wei d, Yu-Shuai Han b, Wen-Jing Yi b, Zhi-Wen Pan e, Ting-Ting Jiang a, Jing Chen b, Hui-Hui Tu b, Zhi-Bin Li b, Yu-Ting Hu a b, Ji-Cheng Li a b

Clinica Chimica Acta Volume 498, November 2019, Pages 135-142

The results suggested that Xanthine, 4-Pyridoxate, and d-glutamic acid may serve as potential biomarkers for pulmonary TB. The present study provides experimental basis for …

Highly selective synthesis of d-amino acids from readily available l-amino acids by a one-pot biocatalytic stereoinversion cascade

Zhang, Danping,Jing, Xiaoran,Zhang, Wenli,Nie, Yao,Xu, Yan

, p. 29927 - 29935 (2019/10/01)

d-Amino acids are key intermediates requ...

Artificial Biocatalytic Cascade with Three Enzymes in One Pot for Asymmetric Synthesis of Chiral Unnatural Amino Acids

Zhou, Haisheng,Meng, Lijun,Yin, Xinjian,Liu, Yayun,Xu, Gang,Wu, Jianping,Wu, Mianbin,Yang, Lirong

, p. 6470 - 6477 (2019/11/02)

Two biocatalytic reactions, transaminati...

6893-26-1 Process route

: 60133-17-7
D-glutamic acid γ-p-nitroanilide

: 6893-26-1,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
D-Glutamic acid

: 100-01-6,104810-17-5
4-nitro-aniline

Conditions

Conditions	Yield
With marine bivalve lysozyme; MOPS buffer; Tapes japonica; at 37 ℃; pH=7.0; Enzyme kinetics;

: 328-50-7
α-ketoglutaric acid

: 2013-12-9,498-18-0
D-norvaline

: 6893-26-1,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
D-Glutamic acid

: 1821-02-9
2-oxopentanoic acid

Conditions

Conditions	Yield
With pyridoxal 5'-phosphate; recombinant Lactobacillus salivarius UCC₁₁₈ D-amino acid aminotransferase; In aq. phosphate buffer; at 30 ℃; for 0.0166667h; pH=7.5; Enzymatic reaction;