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Product Details
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Chemical Properties |
Patents are available for this chemical structure. |
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Uses |
6-methylsulfanyl-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one is a pyrazolopyrimidine derivative that has potential applications in the field of medicinal chemistry due to its ability to inhibit certain enzymes. |
The present invention relates to a New M...
The present invention provides compounds...
… 3-Bromo-6-(methylthio)-1H-pyrazolo[3,4-d] pyrimidine (1) … of 6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one 7 (2.0 … CH 3 CN (180 mL) in a pressure vessel was added a CH 3 CN …
The invention relates to compounds of Fo...
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
![6-(methylsulfanyl)-1H,2H,3H-pyrazolo[3,4-d]pyrimidin-3-one](/upload/2023/6/8964ec38-98a9-4f81-ac13-23091a0f4aa4.png)
6-(methylsulfanyl)-1H,2H,3H-pyrazolo[3,4-d]pyrimidin-3-one
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With hydrazine; at 20 ℃; for 0.0833333h; Microwave irradiation;
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97.1% |
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4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester; With hydrazine; In ethanol;
With sodium hydroxide;
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85% |
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4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester; With hydrazine hydrate; In ethanol; at 20 ℃; for 1h;
With water; sodium hydroxide; at 100 ℃; for 0.333333h;
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Multi-step reaction with 2 steps
1: hydrazine hydrate / ethanol / 1 h / 0 - 25 °C / Inert atmosphere
2: potassium hydroxide; acetic acid / water / 0.25 h / 0 °C / Reflux; Inert atmosphere
With hydrazine hydrate; acetic acid; potassium hydroxide; In ethanol; water;
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Multi-step reaction with 2 steps
1: hydrazine hydrate / ethanol / 1 h / 0 °C
2: water; potassium hydroxide / 1 h / 100 °C
With water; hydrazine hydrate; potassium hydroxide; In ethanol;
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4-hydrazino-2-methylsulfanylpyrimidine-5-carboxylic acid methyl ester
6-(methylsulfanyl)-1H,2H,3H-pyrazolo[3,4-d]pyrimidin-3-one
| Conditions | Yield |
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With acetic acid; potassium hydroxide; In water; at 0 ℃; for 0.25h; Reflux; Inert atmosphere;
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66% |
4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
ethyl 4-hydrazinyl-2-(methylsulfanyl)pyrimidine-5-carboxylate
1-cyclohexyl-3-phenyl-N-propyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine
C21H25N5O2
C22H27N5O2
C18H23N5O
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