34592-47-7

  • Product NameL(-)-Thiazolidine-4-carboxylic acid
  • Molecular FormulaC4H7NO2S
  • Molecular Weight133.171
  • Purity99%
  • Appearancesolid
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Product Details

Quick Details

  • CasNo: 34592-47-7
  • Molecular Formula: C4H7NO2S
  • Appearance: solid
  • Purity: 99%

High Purity L(-)-Thiazolidine-4-carboxylic acid 34592-47-7 In Stock

  • Molecular Formula:C4H7NO2S
  • Molecular Weight:133.171
  • Appearance/Colour:solid 
  • Vapor Pressure:1.58E-05mmHg at 25°C 
  • Melting Point:190-200 °C (dec.)(lit.) 
  • Refractive Index:-200 ° (C=1, 1mol/L NaOH) 
  • Boiling Point:350.3 °C at 760 mmHg 
  • PKA:2.09±0.20(Predicted) 
  • Flash Point:165.7 °C 
  • PSA:74.63000 
  • Density:1.38 g/cm3 
  • LogP:0.06230 

L(-)-Thiazolidine-4-carboxylic acid(Cas 34592-47-7) Usage

Chemical Properties

solid

Uses

L(-)-Thiazolidine-4-carboxylic acid is a proline analogue, which used in peptide coupling reactions. Thiazolidine-4-carboxylic acid (TC) is a cyclic sulfur amino acid, a condensation product of cysteine and formaldehyde.

Definition

ChEBI: An optically active version of thioproline having L-configuration.

InChI:InChI=1/C5H7NO2S/c7-5(8)4-3(9)1-2-6-4/h4,6H,1-2H2,(H,7,8)

34592-47-7 Relevant articles

Actions of a Proline Analogue, L-Thiazolidine-4-Carboxylic Acid (T4C), on Trypanosoma cruzi

Anahí Magdaleno,Il-Young Ahn,Lisvane Silva Paes,Ariel M. Silber

PLoS One, 2009

L-thiazolidine-4-carboxylic acid, a product of the non-enzymatic condensation of equimolar quantities of formaldehyde and L-cysteine to yield the saturated imino acid containing S as a thioether, has the ability to interfere with the utilization of proline for protein synthesis and to mimic proline in its incorporation into proteins. It can be metabolized in both bacterial and mammalian cells.

Synthesis, Antibacterial Activity and DFT Calculations of Some Thiazolidine-4-Carboxylic acid Derivatives and Their Complexes with Cu (II), Fe (II) and VO (II)

F Nawar, R Al-Asadi, D Abid

Egyptian Journal of Chemistry, 2020

This research study explains the synthesis pertaining to certain Thiazolidine-4-carboxylic acid derivatives L2 and L1, which were synthesized in good yield via the reaction of L-Cysteine …

34592-47-7 Process route

formaldehyd
50-00-0,30525-89-4,61233-19-0

formaldehyd

rac-cysteine
921-01-7,3374-22-9,4371-52-2,40143-64-4,40143-66-6,40143-69-9,52-90-4

rac-cysteine

(RS)-4-thiazolidinecarboxylic acid
444-27-9,19291-02-2,34592-47-7,45521-09-3,2756-91-4,6070-92-4,60731-25-1

(RS)-4-thiazolidinecarboxylic acid

Conditions
Conditions Yield
In water; acetic acid; at 30 ℃; for 1h;
93.5%
 
 
In water; for 0.25h; Concentration; Time; Heating;
 
formaldehyd
50-00-0,30525-89-4,61233-19-0

formaldehyd

l-cysteine hydrochloride
52-89-1

l-cysteine hydrochloride

(RS)-4-thiazolidinecarboxylic acid
444-27-9,19291-02-2,34592-47-7,45521-09-3,2756-91-4,6070-92-4,60731-25-1

(RS)-4-thiazolidinecarboxylic acid

Conditions
Conditions Yield
In water; Ambient temperature;
74%

34592-47-7 Upstream products

  • 50-00-0
    50-00-0

    formaldehyd

  • 52-89-1
    52-89-1

    l-cysteine hydrochloride

  • 444-27-9
    444-27-9

    (RS)-4-thiazolidinecarboxylic acid

  • 10318-18-0
    10318-18-0

    DL-cysteine hydrochloride

34592-47-7 Downstream products

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    113613-53-9

    Z-Gly-P(S)

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    5718-87-6

    L'acide L-thiazolidinecarboxylique-4 hydantoine

  • 54323-50-1
    54323-50-1

    (4R)-N-acetylthiazolidine-4-carboxylic acid

  • 51977-23-2
    51977-23-2

    6,8-dioxo-7-phenyl-3-thia-1,7-diazabicyclo<3.3.0>octane

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