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Chemical Properties |
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Uses |
BOC-Glycine is used in the composition of drugs containing Ketoprofen, and Sodium hyaluronate as antiinflammatory agents. BOC-glycine could be effectively obtained using different posttreatment methods. |
InChI:InChI=1/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)/p-1
Boc-glycine and biodegradable safe copolymers by using poly(lactic acid) and FDA-approved poly(ethylene glycol) linked with Boc-glycine … glycol)–Boc-glycine showed absorbance at …
A solution phase synthesis strategy was ...
In this work, three BOC-glycines, BOC- glycine 2,5-furan dimethyl esters, and glycine 2,5-furan dimethyl esters were prepared by changing different experimental contents, and they were characterized using FTIR and TG, etc. The results showed that BOC-glycine could be prepared using three different posttreatment methods, differing only in purity.
tert-butoxycarbonylglycine p-nitrophenylester
BOC-glycine
4-nitro-phenol
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With water; In acetonitrile; Rate constant; other solvent;
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With borax buffer; water; at 25 ℃; pH=8.7; Kinetics;
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N-(tert-butoxycarbonyl)glycine methyl ester
BOC-glycine
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With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 50 ℃; for 1h;
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93% |
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N-(tert-butoxycarbonyl)glycine methyl ester; With methanol; sodium hydroxide; water; at 20 ℃; for 1h;
With potassium hydrogensulfate; In water;
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tert-Butyl 4-nitrophenyl carbonate
glycine
phosgene
GlyOEt*HCl
N-tert-butoxycarbonyl-glycyl=>phenylalanyl=>glycine ethyl ester; N-tert-butoxycarbonyl-glycyl=>L-phenylalanyl=>glycine ethyl ester
glycylphenylalanine
Boc-Gly-ODNP
tert-butoxycarbonylglycine p-nitrophenylester
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