What is the N-Acetyl-L-phenylalanine?

N-Acetyl-L-phenylalanine is white to off-white fine cryst. powder or needles, while it's Molecular Formula is C11H13NO3. white to off-white fine cryst. powder or needles N-Acetyl-L-phenylalanine is an protected analogue of L-Phenylalanine (P319415), an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.

What is the CAS number for N-Acetyl-L-phenylalanine?

The CAS number of N-Acetyl-L-phenylalanine is 2018-61-3.

What is the N-Acetyl-L-phenylalanine?

N-Acetyl-L-phenylalanine is white to off-white fine cryst. powder or needles, while it's Molecular Formula is C11H13NO3. white to off-white fine cryst. powder or needles N-Acetyl-L-phenylalanine is an protected analogue of L-Phenylalanine (P319415), an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.

What is the CAS number for N-Acetyl-L-phenylalanine?

The CAS number of N-Acetyl-L-phenylalanine is 2018-61-3.

Buy Quality N-Acetyl-L-phenylalanine 2018-61-3 Powder

Product Details

Quick Details

CasNo： 2018-61-3
Molecular Formula： C₁₁H₁₃NO₃
Appearance： white to off-white fine cryst. powder or needles
Purity： 99%

Buy Quality N-Acetyl-L-phenylalanine 2018-61-3 Powder

Molecular Formula:C11H13NO3
Molecular Weight:207.229
Appearance/Colour:white to off-white fine cryst. powder or needles
Vapor Pressure:4.96E-09mmHg at 25°C
Melting Point:171-173 °C(lit.)
Refractive Index:40 ° (C=5, MeOH)
Boiling Point:453.9 °C at 760 mmHg
PKA:3.56±0.10(Predicted)
Flash Point:228.3 °C
PSA：66.40000
Density:1.199 g/cm³
LogP:1.20930

N-Acetyl-L-phenylalanine(Cas 2018-61-3) Usage

Chemical Properties	white to off-white fine cryst. powder or needles
Uses	It is an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of aspartame. It is applied as an antidepressant. N-Acetyl-L-phenylalanine can be used as a reactant to synthesize: N-acetyl phenylalanine methyl ester by esterification reaction with methanol using Mukaiyama′s reagent. Acetylaminocyclohexane propanoic acid by rhodium-catalyzed hydrogenation reaction.
Definition	ChEBI: The N-acetyl derivative of L-phenylalanine.
General Description	N-Acetyl-L-phenylalanine is an acetyl analog of L-phenylalanine. It is widely used as a reactant to synthesize methyl or ethyl esters of N-acetyl-L-phenylalanine, which are employed as versatile building blocks in peptide synthesis.
Purification Methods	N-Acetyl-L-phenylalanine is recrystallised from H2O, 20% MeOH/H2O, or CHCl3; dry and store it at 4o. The (DL)-isomer crystallises from H2O, Me2CO, EtOAc, or CHCl3 with m 152-154o and the solubilities in w% at 25o are 0.73 (H2O), 4.3 (Me2CO), 0.79 (EtOAc) and 0.34 (CHCl3)

InChI:InChI=1/C11H13NO3/c1-8(13)12-10(11(14)15)7-9-5-3-2-4-6-9/h2-6,10H,7H2,1H3,(H,12,13)(H,14,15)/p-1/t10-/m0/s1

2018-61-3 Relevant articles

Metabolomics reveals arbuscular mycorrhizal fungi-mediated tolerance of walnut to soil drought

Ying-Ning Zou, Qiu-Yun Qin, Wen-Ya Ma, Li-Jun Zhou, Qiang-Sheng Wu, Yong-Jie Xu, Kamil Kuča, Abeer Hashem, Al-Bandari Fahad Al-Arjani, Khalid F. Almutairi & Elsayed Fathi Abd-Allah

BMC Plant Biology volume 23, Article number: 118 (2023)

Among them, oxidative phosphorylation and phenylalanine metabolism and biosynthesis were triggered by AMF in response to WW and DS, where N-acetyl-L-phenylalanine was …

Preparation and performance of a poly (ethyleneimine) embedded N-acetyl-L-phenylalanine mixed-mode stationary phase for HPLC

Meijun Wan a, Qiurong Luo a, Xiujun Ren a, Yunchao Zheng a, Die Gao a, Qifeng Fu a, Fengjiao Zu a d, Zhining Xia b, Lujun Wang a c

Microchemical Journal Volume 157, September 2020, 105021

In this paper, a new multifunctional stationary phase was synthesized by grafting PEI and N-acetyl-L-phenylalanine onto the surface of silica gel, named Sil-PEI-APH.

2018-61-3 Process route

: 14009-94-0
N-acetyl-L-phenylalanine 4-nitrophenyl ester

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 2018-61-3
(S)-2-acetylamino-3-phenylpropanoic acid

Conditions

Conditions	Yield
PalHis; PalHis + 2C₁₄N₂C₁Br; In water; acetonitrile; at 25 ℃; Rate constant; furhter bilayer catalytic systems; k_cat;
With N^α-tetradecanoyl-L-histidine; In water; acetonitrile; at 10 ℃; Rate constant; Kinetics; Thermodynamic data; ΔH(excit.), ΔS(excit.); Tris-KCl buffer, didodecyldimethylammonium bromide; other nucleophiles and surfactants, other temp.;
With water; poly(iminomethylene); cetylpyridinium chloride; at 23 ℃; Rate constant; pH 5.6; different poly(iminomethylene) 1-cetylpyridinium complexes catalysts and pH-s;
With Z-L-Leu-L-His-L-Leu; Tris buffer; N,N-didodecyl-N,N-dimethylammonium bromide; In acetonitrile; at 24.9 ℃; Rate constant; pH: 7.68, μ = 0.15 (KCl); other peptide catalyst; binding constants K_b/N;