7524-50-7

  • Product NameL-Phenylalanine methyl ester hydrochloride
  • Molecular FormulaC10H14ClNO2
  • Molecular Weight215.68
  • Purity99%
  • Appearancewhite to off-white fine crystalline powder
Inquiry

Product Details

Quick Details

  • CasNo: 7524-50-7
  • Molecular Formula: C10H14ClNO2
  • Appearance: white to off-white fine crystalline powder
  • Purity: 99%

Buy Quality Pharmaceutical Intermediates L-Phenylalanine methyl ester hydrochloride 7524-50-7

  • Molecular Formula:C10H14ClNO2
  • Molecular Weight:215.68
  • Appearance/Colour:white to off-white fine crystalline powder 
  • Vapor Pressure:0.01mmHg at 25°C 
  • Melting Point:158-162 °C(lit.) 
  • Refractive Index:38 ° (C=2, EtOH) 
  • Boiling Point:264.2 °C at 760 mmHg 
  • Flash Point:126 °C 
  • PSA:52.32000 
  • LogP:2.23170 

Methyl L-phenylalaninate hydrochloride(Cas 7524-50-7) Usage

Chemical Properties

white to off-white fine crystalline powder

Uses

Protected (S) enantiomer of the amino acid Phenylalanine.

InChI:InChI=1/C10H13NO2/c1-13-10(12)9(11)7-8-5-3-2-4-6-8/h2-6,9H,7,11H2,1H3/p+1/t9-/m0/s1

7524-50-7 Relevant articles

Microwave-Assisted Ruthenium- and Rhodium-Catalyzed Couplings of α-Amino Acid Ester-Derived Phosphinamides with Alkynes

Li, Xue-Hong,Gong, Jun-Fang,Song, Mao-Ping

supporting information, (2021/12/23)

Two different types of new phosphinamide...

Application of proteasome inhibitor in inhibition of novel coronavirus

-

Paragraph 0162-0165, (2021/06/22)

The invention provides application of a ...

C2 symmetric copper (II) complexes of L-valine and L-phenyl alanine based chiral diimines for catalytic asymmetric Henry reaction

Ananthi, Nallamuthu,Johnson, S. Jesu,Kumar, K. Vinoth,Nixon, Peter Daniel

supporting information, (2021/05/19)

New C2 symmetric chiral diimines were sy...

Modular Fragment Synthesis and Bioinformatic Analysis Propose a Revised Vancoresmycin Stereoconfiguration

Adamek, Martina,Essig, Sebastian,Kurz, Michael,Menche, Dirk,Sch?nenbroicher, Max,Seul, Maximilian,Spindler, Stefanie,Wingen, Lukas M.,Ziemert, Nadine

supporting information, p. 1175 - 1180 (2021/01/13)

Elaborate fragments of the proposed ster...

7524-50-7 Process route

2-methyl-propan-1-ol
78-83-1

2-methyl-propan-1-ol

(S)-N-acetylphenylalanine
3618-96-0

(S)-N-acetylphenylalanine

2-methylpropyl acetate
110-19-0

2-methylpropyl acetate

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
Conditions Yield
(S)-N-acetylphenylalanine; With triphenyl phosphite; chlorine; triethylamine; In tetrahydrofuran; at -30 ℃;
2-methyl-propan-1-ol; In tetrahydrofuran; at -30 - 20 ℃;
With water;
95%
L-phenylalanine
63-91-2,25191-15-5,658-69-5,67675-33-6

L-phenylalanine

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
Conditions Yield
With thionyl chloride; In methanol;
100%
With thionyl chloride; In methanol; at 0 - 20 ℃;
100%
With thionyl chloride; In methanol;
98%
With thionyl chloride; In methanol; diethyl ether;
95%
In methanol; benzene; for 4h; Ambient temperature;
42%
With hydrogenchloride;
Multi-step reaction with 2 steps
1: thionyl chloride
With thionyl chloride;
With hydrogenchloride; methanol; In di-isopropyl ether; at 55 ℃; for 0.0833333h; Heating / reflux;
With thionyl chloride; In methanol;
With hydrogenchloride; In methanol; toluene;

7524-50-7 Upstream products

  • 67-56-1
    67-56-1

    methanol

  • 63-91-2
    63-91-2

    L-phenylalanine

  • 13200-85-6
    13200-85-6

    N-formyl-L-phenylalanine

  • 126027-31-4
    126027-31-4

    DL-β-chloro-β-phenylalanine hydrochloride

7524-50-7 Downstream products

  • 4833-87-8
    4833-87-8

    2?(1,3?dioxoisoindolin?2?yl)acetyl methyl phenylalaninate

  • 17274-89-4
    17274-89-4

    (S)-2-(nicotinamido)-3-phenylpropanoic acid

  • 18598-80-6
    18598-80-6

    methyl N-trityl-(S)-phenylalaninate

  • 6206-42-4
    6206-42-4

    N-benzyloxycarbonylglycyl-L-phenylalanine methyl ester

;