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Product Details
Chemical Properties |
White powder |
Uses | N,1-Di-Boc-L-histidine dicyclohexylammonium salt has various applications in the pharmaceutical industry, including as a starting material for the synthesis of various drugs and as a reagent in organic chemistry. It is also used in research studies to investigate the effects of amino acid derivatives on biological systems. |
IUPAC Name: N-cyclohexylcyclohexanamine;(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]imidazol-4-yl]propanoic acid
Isomeric SMILES: CC(C)(C)OC(=O)N[C@@H](CC1=CN(C=N1)C(=O)OC(C)(C)C)C(=O)O.C1CCC(CC1)NC2CCCCC2
InChIKey: WBGMQHNUPJENDC-MERQFXBCSA-N
InChI: InChI=1S/C16H25N3O6.C12H23N/c1-15(2,3)24-13(22)18-11(12(20)21)7-10-8-19(9-17-10)14(23)25-16(4,5)6;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h8-9,11H,7H2,1-6H3,(H,18,22)(H,20,21);11-13H,1-10H2/t11-;/m0./s1
Boc-His(Boc)-OH·DCHA (1) (2.14 g, 4 mmol) and Gly-OBzl·TsOH (2) (1.34 g, 4 mmol) in acetonitrile (40 mL) under an argon atmosphere. Then, the reaction mixture was stirred at room …
di-tert-butyl dicarbonate
N-cyclohexyl-cyclohexanamine
L-histidine
Boc-His(Boc)-OH dicyclohexylamine salt
Conditions | Yield |
---|---|
With triethylamine; 1) water, dioxane, 30 to 45 deg C; 2) diethyl ether;
|
75% |
N-[2-N-acetylamino-4-(3-aminophenyl)thiazole]propargylglycinamide
Boc-His(Boc)-OH dicyclohexylamine salt
N-[2-N-acetylamino-4-(3-aminophenyl)thiazole]-[Nα,Nimidazole(di-tert-butoxycarbonyl)]histidylglycinamide
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;
|
94% |
di-tert-butyl dicarbonate
N-cyclohexyl-cyclohexanamine
L-histidine
Nα-t-butoxycarbonyl-Nim-t-butoxycarbonylhistidyl-leucyl-leucylvalyl-O-benzyltyrosyl-O-benzylserine benzyl ester
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